The PerioSciences line of AO Pro Toothpaste was developed by forward-thinking researchers who moved beyond the simple approach of eliminating bacteria with alcohol. This method often creates dry mouth conditions that allow bacteria to flourish. Instead, our toothpaste focuses on newer technologies and ingredients like antioxidants to work in concert with the natural defenses in your mouth. Toothpaste with antioxidants is gentle on oral tissue but tough on bacteria and other common problems.